Research Fellow (ORISE) at US Food & Drug Administration
I am currently applying my background with pluripotent stem cell differentiations to derive both heart and liver lineages for experimental use with multiple drug modeling platforms, from single cell analysis to organ-on-a-chip devices. This research in the Division of Applied Regulatory Science focuses on bridging the gap between scientific innovation and product review. For more information, see CV and Publications.
I completed my doctoral research at Boston University, as part of the Graduate Program for Genetics and Genomics and as a member of the Center for Regenerative Medicine (CReM) as well as the Pulmonary Center. My dissertation research focused on thyroid and lung development, utilizing both pluripotent stem cells and mouse models. My dissertation research integrated strategies of directed differentiation and transcriptional overexpression to achieve highly efficient derivation of functionally mature thyrocyte organoids. See Publications for more.
Pluripotent Stem Cells - Directed Differentiation - Developmental Biology - Engineered Cellular Systems - Drug Safety & Efficacy - Drug Regulation - Context of Use - Heart Development - Liver Development - Lung Development - Thyroid Development - Endodermal Derivatives - Epithelial Cells - Cell Culture - Transcriptional Regulation of Development - Cell Fate Decisions - Transcriptional Networks - Reprogramming - Direct Conversion - Gene Editing - Functional Assays - Disease Modeling - Autologous Cell Therapy - Organ Regeneration and Repair - Experimental Design